Barzilai University Medical Center

120 Research Day 2020 Barzilai University Medical Center 86 CENTRAL RETINAL VEIN OCCLUSION IN EARLY PREGNANCY Reuven Russell Pokroy Department of Ophthalmology, Barzilai University Medical Center, Ashkelon Background Central retinal vein occlusion (CRVO) is relatively rare under the age of 40, which makes it unusual in pregnancy. Anti-VEGF treatment has become the gold standard for initial treatment of CRVO. Because of the rarity of CRVO in pregnancy and the potential teratogenic effect of anti-VEGF on the developing embryo, little data is available in the published literature regarding the management of CRVO in pregnancy. Hypothesis The clinical course and management of CRVO in pregnancy significantly differs from that of patients older than 65 with CRVO. Objectives This case report aims to highlight the different treatment options and describe the interesting clinical course of a young woman in early pregnancy with very poor vision due to recent-onset CRVO. Results A 39-year-old woman with mild gestational diabetes mellitus presented at 6 weeks gestation with visual acuity of 6/60. Examination revealed CRVO with severe cystoid macular edema with OCT central retinal thickness of 1431 um. Visual acuity in the fellow eye and intraocular pressure in both eyes were normal. The clinical course was documented with multiple OCT scans of the retina and clinical examinations. Conclusions With close monitoring, and good clinical decision-making, a good visual outcome can be attained in CRVO in early pregnancy with severe macular edema and poor vision.