Dr. Levy Vardy Ronen
Head of Internal Medicine Department C
Medical Education
1991-1997 Semmelweis University of Medicine, Budapest. Medicine.
Other Educations
1987-1990 BSc in Life Sciences, Hebrew University, Jerusalem, Israel
Specialty
Internal Medicine
Nephrology and Hypertension
Positions and clinical experience
1999-2003 Residency in Internal medicine, Hadassah Medical Center, Jerusalem, Israel
2005-2007 Residency in Nephrology and Hypertension, Hadassah Medical Center,
Jerusalem, Israel
2007-2016 Senior physician, Nephrology and Hypertension, Hadassah Medical Center,
Jerusalem, Israel
2017 – Current: Senior physician, Nephrology and Hypertension, Barzilai Medical Center,
Ashkelon, Israel
2023- Current: Head of the Internal Medicine department C, Barzilai Medical Center,
Ashkelon, Israel
Continuing Medical Education
2018 – Certificate of Good Clinical Practice Course
Membership of Professional Organizations in Israel and Abroad
♦ Israel Medical Association
♦ State Physicians Organizaition
♦ Israel Society of Internal Medicine
♦ Israel Society of Nephrology and Hypertension
Academic Appointments
2005- 2010 Clinical instructor in Internal Medicine
2011- 2016 Lecturer in Internal Medicine at the Hebrew University School of Medicine in
Jerusalem
2017-Current: Lecturer in Internal Medicine, School of Medicine, Ben Gurion University of
the Negev, Beer Sheva', Israel
Teaching Experience
1999-2003 Physical diagnosis for medical students [4th (course No 96713) and 6th years]
1999-2016 Internal Medicine for medical students (4th and 6th years), School of
Medicine, Hebrew University, Jerusalem, Israel
2005-2016 Introductory course in internal medicine to 4th year medical students-
nephrology. Course No 96713, School of Medicine, Hebrew University,
Jerusalem, Israel
2005-2016 Nephrology for 6th year medical School of Medicine, Hebrew University,
Jerusalem, Israel
2009- 2016 Molecular mechanisms in kidney physiology in health and disease, course No
94412, for MSc and PhD students, School of Medicine, Hebrew University,
Jerusalem, Israel
2010- 2016 Pathology of Diseases, course No 64861, for 3rd year pharmacy students,
School of Pharmacy, Hebrew University, Jerusalem, Israel
2017- 2018 Nephrology course for students of the International School of Medicine, Health
Science faculty, Ben-Gurion University of the Negev, Beer Sheva', Israel
2017- 2020 Nephrology for 2nd year pharmacy students, Pharmacy School, Health Science
faculty, Ben-Gurion University of the Negev, Israel
2018- 2020 Advanced nursing care, Barzilai University Medical Center
2017- Current: Nephrology for 3rd year medical students, School of Medicine, Health
Science faculty, Ben-Gurion University in the Negev, Beer Sheva', Israel
2017- Current: Nephrology rounds for 5th year medical students, School of Medicine, Health
Science faculty, Ben-Gurion University in the Negev, Beer Sheva', Israel
Awards
Æ 2003 Certificate of excellent medical instructor of the Faculty of Medicine of the Hebrew
University of Medicine
Æ 2003- 2005 Physician Research Scholarship
Æ 2007 Award of the Faculty of Medicine of the Hebrew University and Hadassah Medical
Center for excellence in clinical work.
Æ 2008 Certificate of excellent medical instructor of the Faculty of Medicine of the Hebrew
University of Medicine
Æ 2011 Israeli Society of Nephrology scholarship for research on the regulation of FGF23 in
states of chronic kidney failure
Æ 2013 Letter of appreciation for excellence in teaching from the dean of the Hebrew
University of Medicine
Æ2016 Bridging Fund Grant: Mechanism of regulation of fibroblast growth factor 23 in
experimental models of acute and chronic kidney disease
Membership in National and International Committees
2008-2012 Member of the committee for writing the final examinations in Internal Medicine for the 6th year students, the Faculty of Medicine, Hebrew University, Jerusalem, Israel.
Scientific Publications
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Chana Yagil, Ronen Varadi-Levi, Chen Ifrach and Yoram Yagil., Dysregulated UPR and ER Stress Related to a Mutation in the Sdf2l1 Gene Are Involved in the Pathophysiology of Diet-Induced Diabetes in the Cohen Diabetic Rat. International Journal of Molecular Sciences 2023 24, 1355 2.
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Larissa Lebedev, Marina Sapojnikov, Alexander Vechsler, Ronen Levi-Vardi, Doron Zamir, Ana Tovar, Nomy Levin-Yaina, Shlomo Fytlovich, Yoram Yagil., Minimal Change Disease Following the Pfizer-BioNTech COVID-19 Vaccine. American Journal of Kidney Diseases 2021 78(1): 142-145
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Chana Yagil, Ronen Varadi-Levi, Yoram Yagil., A novel mutation in the NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4 (Ndufa4) gene links mitochondrial dysfunction to the development of diabetes in a rodent model. Disease Models & Mechanisms 2018 11: 1-9
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Durlacher-Betzer K, Hassan A, Levi R, Axelrod J, Silver J, Naveh-Many T., Interleukin-6 contributes to the increase in fibroblast growth factor 23 expression in acute and chronic kidney disease. Kidney Int. 2018 Aug;94(2):315-325
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Alia Hassan, Karina Durlacher, Justin Silver, Tally Naveh-Many and Ronen Levi., The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia. Am J Physiol Renal Physiol 2016 Feb 1;310(3): F217-21
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Khoury T, Yosha L, Abu Ramieleh A, Schneider R, Wolf DG, Levi R., A heart breaking case of rapidly developing severe hemophagocytic syndrome secondary to chronic active EBV infection; a case report and review of the literature. Journal of Clinical Virology. 2015 67: 14-16
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Meir T, Levi R, Lieben L, Libutti S, Carmeliet G, Bouillon R, Silver J, Naveh-Many T., Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the VDR in parathyroid physiology. Am J Physiol Renal Physiol. 2009 Aug; (Epub ahead of print). 3.9
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Ronen Levi, Iddo Z. Ben-Dov, Vardit Lavi-Moshayoff, Maya Dinur, David Martin, Tally Naveh-Many, Justin Silver., Increased PTH gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: Correlation with post-translational modification of the trans acting factor AUF1. Journal of the American Society of Nephrology 2006 17(1): 107-112. 7.63
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Osnat Bell, Elena Gaberman, Rachel Kilav, Ronen Levi, Keith B. Cox, Jeffery D. Molkentin, Justin Silver, and Tally Naveh-Many., The Protein Phosphatase Calcineurin Determines Basal Parathyroid Hormone Gene Expression. Mol Endocrinol 2005 19: 516-526. 5.2
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Moz Yulia, Levi Ronen, Lavi Moshayoff V, Cox KB, Molkentin JD, Siver J, Naveh-Many T., Calcineurin A beta is central to the expression of the renal type II Na/Pi co-transporter gene and to the regulation of renal phosphate transport. J Am Soc Nephrol. 2004 Dec;15(12):2972-80. 7.6
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Moz Yulia, Levi Ronen, Lavi Moshayoff V, Cox KB, Molkentin JD, Siver J, Naveh-Many T., Protein-RNA interactions determine the stability of the renal NaPi-2 cotransporter mRNA and its translation in hypophosphatemic rats. J Biol Chem. 1999 Sep 3: 274(36):25266-72. 5.3
Reviews
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Levy Vardy Ronen, Yagil Yoram: Hypertension as a cause of kidney disease – Is it true? Harefuah, 2020;159(12):887-891
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Ronen Levi, Yoram Yagil., Vitamin D, hypertension and ischemic stroke: an unresolved relationship. Hypertension, 2017 Sep: 1-3
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Khoury T, Tzukert K, Abel R, Abu Rmeileh A, Levi R, Ilan Y., The gut-kidney axis in chronic renal failure: A new potential target for therapy. Hemodial Int. 2016 Sep 16 (Epub ahead of print)
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Levi R, Silver J., Vitamin D supplementation after kidney transplantation. How much vitamin D should we prescribe? Kidney Int. 2009 Mar; 75(6):576-578. Review. 6
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Ronen Levi, Anca Gal-Moscovici., Renal osteodystrophy in peritoneal dialysis: special considerations. Peritoneal dialysis international. 2008, 28: S11-S19
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Silver J, Levi R., Regulation of PTH synthesis and secretion relevant to the management of secondary hyperparathyroidism in chronic kidney disease. Kidney Int. Suppl. 2005 Jun;(95): S8-12. Review. 6
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Ronen L, Silver J., Pathogenesis of parathyroid dysfunction in end-stage kidney disease. Pediatr Nephrol. 2005 Mar;20(3):342-5. Epub 2004 Nov 10. Review. 2.4
Chapters in Books
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Yoram Yagil, Ronen Levi Varadi, Chana Yagil, Genomic research in rat models of kidney disease, Methods in molecular biology (not published yet)
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Ronen L, Silver J., Hypercalcemia in Oxford Textbook of Endocrinology and Diabetes 2nd edition, September 25, 2011. Bilezikian J, editor. Oxford University Press, Oxford, p 642
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Ronen L, Hyperparathyroidism in Elsevier's First Consult- evidence based answers for the point of care, Sept 2010
Presentations at National and International Conferences
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Poster at the American Society of Nephrology Annual Meeting Nov 2016: "IL-6 acts on bone to increase FGF-23 expression in acute and chronic renal failure and in vitro"
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American Society of Nephrology Annual Meeting Nov 2015. Lecture on: "The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia"
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Israeli Society of Nephrology Annual Meeting March 2015. Lecture on: "FGF23 in Acute Kidney Injury"
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Israeli Society of Nephrology Board Review Oct. 2010. Lecture on: "Potassium Disorders- clinical emergencies"
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Israeli Society of Nephrology Annual Meeting May 2010. Lecture on: "De Novo Glomerulonephritis in Kidney Transplant Patients- Case Presentation and Review of the Literature"
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American Society of Nephrology Annual Meeting 2004. Lecture on: "The Protein Phosphatase Calcineurin Aβ Determines PTH Gene Expression" Oral presentation
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Israeli Society of Nephrology Annual Meeting 2003. Lecture on: "Secondary hyperparathyroidism and regulation of PTH gene expression in a rat model of renal failure"